Author

J. J. Saez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

J. Diaz· 2 shared M.-I. Yuseff· 2 shared A. E. Zucchetti· 1 shared A. Soza· 1 shared C. Hivroz· 1 shared C. Quiroga· 1 shared C. Rivas· 1 shared E. R. Gomes· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

J. Diaz

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3 papers

Recent·Most cited

B cells adapt their nuclear morphology to organize the immune synapse and help antigen extraction

R. Ulloa, O. Corrales, F. Cabrera, J. Jara-Wilde, J. J. Saez, C. Rivas, J. Lagos, S. Härtel, C. Quiroga, E. R. Gomes, M.-I. Yuseff, J. Diaz

This study shows that B cells adapt nuclear morphology to organize the immune synapse and facilitate antigen extraction by repositioning the nucleus and coordinating actin and lysosome dynamics.

bioRxiv · Apr 20, 2021 · PreprintCell Biology

Ecm29-dependent proteasome localization regulates cytoskeleton remodeling at the immune synapse

J. Ibanez-Vega, F. Del Valle Batalla, J. J. Saez, J. Diaz, A. Soza, M.-I. Yuseff

This study shows that Ecm29 regulates proteasome localization, which in turn controls actin dynamics and lysosome positioning during immune synapse formation in B cells.

bioRxiv · Dec 23, 2020Cell Biology

Retrograde And Anterograde Transport Of LAT-Vesicles During The Immunological Synapse Formation: Defining The Finely-Tuned Mechanism

J. J. Saez, S. Dogniaux, M. Shafaq-Zadah, L. Johannes, C. Hivroz, A. E. Zucchetti

The paper investigates retrograde and anterograde transport of LAT-vesicles during immunological synapse formation, identifying specific proteins regulating each pathway.

bioRxiv · Dec 17, 2020Cell Biology