Author

J. J. Shaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. Sharma· 1 shared B. J. Horton· 1 shared C. B. Angeli· 1 shared C. E. Chalfant· 1 shared D. Brandt-Almeida· 1 shared D. F. Claxton· 1 shared D. J. Feith· 1 shared D. Martins· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Sharma

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

J. Ung, S.-F. Tan, T. E. Fox, J. J. Shaw, M. Taori, B. J. Horton, U. Golla, A. Sharma, Z. M. Szulc, H.-G. Wang, C. E. Chalfant, M. C. Cabot, D. F. Claxton, T. P. Loughran, D. J. Feith

This study evaluates the anti-leukemic effects of LCL-805, an acid ceramidase inhibitor, in AML cell lines and patient samples, showing it promotes iron-dependent cell death by antagonizing Akt signaling.

bioRxiv · Oct 21, 2023Cancer Biology

Leishmaniinae: evolutionary inferences based on protein expression profiles (PhyloQuant) congruent with phylogenetic relationships among Leishmania, Endotrypanum, Porcisia, Zelonia, Crithidia, and Leptomonas

S. N. Mule, E. V. Aleman, L. R. Fernandes, J. S. Saad, G. S. de Oliveira, D. Martins, C. B. Angeli, D. Brandt-Almeida, M. Cortez, M. R. Larsen, J. J. Shaw, M. M. G. Teixeira, G. Palmisano

The paper infers evolutionary relationships among Leishmaniinae parasites using protein expression profiles, finding results congruent with established DNA-based phylogeny.

bioRxiv · Sep 22, 2023 · PreprintEvolutionary Biology