Author

J. J. T. H. Roelofs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

A. Tammaro· 2 shared L. Butter· 2 shared A. A. van der Veen· 1 shared A. C. I. van Steen· 1 shared A. C. Parra· 1 shared A. Jongejan· 1 shared E. Aronica· 1 shared E. G. Daniels· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPathology

A. Tammaro

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PathologybioRxivPreprintAug 29, 2023

Treatment with a selective histone deacetylase (HDAC) 1 and 2 inhibitor in aged mice rejuvenates multiple organ systems

A. Tammaro, E. G. Daniels, I. M. Hu…·G. E. Janssens

This paper identifies a selective HDAC1/2 inhibitor, Cmpd60, that rejuvenates multiple organ systems in aged mice through transcriptional effects mimicking genetic longevity interventions.

DOI 10.1101/2023.08.29.555280

mousebulk RNA-seq

𝕏 PostBluesky

PathologybioRxivPreprintAug 17, 2023

Air Pollution Aggravates Renal Ischemia-Reperfusion-Induced Acute Kidney Injury

T. R. Sanches, A. C. Parra, P. Sun…·A. Tammaro

This study shows that PM2.5 exposure worsens IRI-induced AKI in mice by increasing tubular damage, immune activation, and fibrosis markers.

DOI 10.1101/2023.08.17.553734

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 14, 2022

Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM1

M. L. B. Grönloh, J. J. G. Arts, S. Palacios Martinez…·J. D. van Buul

The paper identifies endothelial transmigration hotspots that limit vascular leakage by heterogeneous ICAM-1 expression, showing that ICAM-1 distribution determines hotspot location and function.

DOI 10.1101/2022.01.14.476297

humanproteomics

𝕏 PostBluesky