Author

J. Kargl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Z. N. Mihalic· 4 shared A. Heinemann· 3 shared O. Kindler· 3 shared A. Santiso· 2 shared C. Wadsack· 2 shared G. Marsche· 2 shared J. Pollheimer· 2 shared N. Cosic-Mujkanovic· 2 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

Z. N. Mihalic

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Myeloperoxidase promotes a tumorigenic microenvironment in non-small cell lungcancer

P. Valadez-Cosmes, M. Kathrin, O. Kindler, N. Cosic-Mujkanovic, A. Lueger, S. Raftopoulou, M. Kienzl, Z. N. Mihalic, A. Santiso, A. Sarsembayeva, L. Brcic, J. Lindenmann, W. Sattler, A. Heinemann, R. Schicho, , J. Kargl

The paper shows high MPO expression in NSCLC predicts poor outcomes and MPO deficiency in mice enhances anti-tumorigenic immune infiltration, suggesting MPO promotes a pro-tumorigenic microenvironment.

bioRxiv · Jan 28, 2023Cancer Biology

Myeloperoxidase enhances the migration of human choriocarcinoma JEG-3 cells

Z. N. Mihalic, T. Kloimboeck, N. Cosic-Mujkanovic, P. Valadez-Cosmes, K. Maitz, O. Kindler, C. Wadsack, A. Heinemann, G. Marsche, M. Gauster, J. Pollheimer, J. Kargl

This study shows that myeloperoxidase enhances migration of JEG-3 choriocarcinoma cells by internalization and activity, suggesting a role in EVT function during pregnancy.

bioRxiv · Jan 28, 2023 · PreprintCell Biology

Gestational diabetes mellitus dysregulates the PD-1/PD-L1 axis at the feto-maternal interface

Z. N. Mihalic, O. Kindler, S. Raftopoulou, A. Santiso, C. Wadsack, A. Heinemann, J. Kargl

The paper examines immune changes at the fetal-maternal interface in GDM, obesity, and healthy pregnancies, finding dysregulated PD-1/PD-L1 axis and reduced Treg infiltration in GDM.

bioRxiv · Jan 25, 2023 · PreprintImmunology

The human placenta shapes the phenotype of decidual macrophages.

S. Vondra, A.-L. Hoebler, A. I. Lackner, J. Raffetseder, Z. N. Mihalic, A. Vogel, L. Saleh, V. Kunihs, P. Haslinger, M. Wahrmann, H. Husslein, R. Oberle, J. Kargl, S. Haider, P. Latos, , J. Pollheimer

This study identifies distinct macrophage phenotypes in human decidua basalis and parietalis, showing that placenta-derived trophoblasts induce a pregnancy-tolerant macrophage phenotype.

bioRxiv · Mar 29, 2022Immunology