Transcriptional heterogeneity in cancer-associated regulatory T cells is predictive of survival.
N. Borcherding, K. K. Ahmed, A. P. Voigt, A. Vishwakarma, R. Kolb, P. Kluz, G. Pandey, K. N. Gibson-Corley, J. Klesney-Tait, Y. Zhu, J. Lu, J. Lu, X. Huang, J. Cheng, S. G. Zheng, , W. Zhang
The paper identifies transcriptional subtypes of tumor-infiltrating regulatory T cells and shows that a CD177+ subset predicts poorer survival in renal clear cell carcinoma and other cancers.
bioRxiv · Nov 26, 2018 · PreprintCancer Biology