Author

J. Kloehn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

D. Soldati-Favre· 2 shared A. Krishnan· 1 shared E. Varesio· 1 shared L. Izquierdo· 1 shared M. Lunghi· 1 shared M. P. Alberione· 1 shared O. Vadas· 1 shared S. Rudaz· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

D. Soldati-Favre

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2 papers

Recent·Most cited

N -acetylglucosamine supplementation fails to bypass the critical acetylation of glucosamine-6-phosphate required for Toxoplasma gondii replication and invasion

M. P. Alberione, V. Gonzalez-Ruiz, S. Rudaz, D. Soldati-Favre, L. Izquierdo, J. Kloehn

This study shows that N-acetylglucosamine supplementation cannot restore UDP-GlcNAc levels or function in T. gondii when GNA1 is depleted, highlighting the critical role of GlcN6P acetylation in parasite replication and invasion.

bioRxiv · Jan 18, 2024 · PreprintMicrobiology

Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondii

M. Lunghi, J. Kloehn, A. Krishnan, E. Varesio, O. Vadas, D. Soldati-Favre

This study shows that pantothenate biosynthesis is critical for chronic Toxoplasma gondii infection, while CoA synthesis is essential for acute stages.

bioRxiv · Oct 4, 2021Microbiology