J. Kowalski

Non-B DNA-Informed Mutation Burden as a Marker of Treatment Response and Outcome in Cancer

This paper introduces two novel markers, nbTMB and mlTNB, to improve prediction of treatment response and outcomes in cancer by incorporating non-B DNA mutation information.

Quantifying the Prevalence of Non-B DNA Motifs as a Marker of Non-B Burden in Cancer using NBBC

The paper introduces NBBC, a web-based tool for quantifying non-B DNA motifs in cancer, and provides a detailed protocol for its use in analyzing genomic stability and mutation signatures.

Transcription Factor EB (TFEB) activity increases resistance of TNBC stem cells to metabolic stress

This study shows that TFEB enhances TNBC stem cell resistance to metabolic stress by modulating autophagy and the unfolded protein response.

Comprehensive cancer-oriented biobanking resource of human samples for studies of post-zygotic genetic variation involved in cancer predisposition

This paper describes a biobanking resource collecting human samples for studying post-zygotic genetic variation in cancer predisposition, including 23,226 samples from 1,711 patients and controls.

An experimental-mathematical approach to predict tumor cell growth as a function of glucose availability in breast cancer cell lines

The paper develops and validates a mathematical model to predict tumor cell growth based on glucose availability in breast cancer cell lines using experimental data.