Author

K. N. Dalby

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. L. Bohanon· 2 shared T. Kaoud· 2 shared A. Annapareddy· 1 shared A. P. Horton· 1 shared A. Paul· 1 shared A. Piserchio· 1 shared A. Somma· 1 shared C. I. Terrace· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBioengineering

A. L. Bohanon

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Transcription Factor EB (TFEB) activity increases resistance of TNBC stem cells to metabolic stress

C. L. Van Den Berg, M. Soleimani, R. Goyal, A. Somma, T. Kaoud, K. N. Dalby, J. Kowalski, S. G. Eckhardt

This study shows that TFEB enhances TNBC stem cell resistance to metabolic stress by modulating autophagy and the unfolded protein response.

bioRxiv · May 30, 2023Cancer Biology

Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control

D. J. Wible, Z. Parikh, E. J. Cho, M.-D. Chen, S. Mukhopadhyay, K. N. Dalby, S. Varadarajan, S. B. Bratton

This study shows that p38 MAPK inhibitors induce cytoplasmic vacuolation by inhibiting both PIKfyve and p38 MAPKs, revealing an epistatic relationship in endolysosomal fission and volume control.

bioRxiv · Mar 13, 2023Cell Biology

Biomechanical dependence of SARS-CoV-2 infections

A. Paul, S. Kumar, T. Kaoud, M. R. Pickett, A. L. Bohanon, J. Zoldan, K. N. Dalby, S. H. Parekh

This study investigates how lung biomechanical changes with age affect SARS-CoV-2 infection rates using hydrogels and fiber matrices, finding higher infection rates on softer scaffolds resembling younger lungs.

bioRxiv · Feb 17, 2022Bioengineering

Structural Basis for the Calmodulin-Mediated Activation of eEF-2K

A. Piserchio, E. A. Isiroho, K. Long, A. L. Bohanon, E. A. Kumar, N. Will, D. Jeruzalmi, K. N. Dalby, R. Ghose

The paper determines the atomic structure of the calmodulin-eEF-2KTR complex, revealing the mechanism by which calmodulin activates eEF-2K through an allosteric spine.

bioRxiv · Jan 15, 2022 · PreprintBiochemistry

Rapid characterization of spike variants via mammalian cell surface display

K. Javanmardi, C.-W. Chou, C. I. Terrace, A. Annapareddy, T. S. Kaoud, Q. Guo, J. Lutgens, H. Zorkic, A. P. Horton, E. C. Gardner, G. Nguyen, D. R. Boutz, J. Goike, W. N. Voss, H.-C. Kuo, , I. J. Finkelstein

This study characterizes SARS-CoV-2 spike variants by assessing their expression, ACE2 binding, and neutralizing antibody recognition across multiple variants.

bioRxiv · Mar 30, 2021Biochemistry