Author

J. L. Chlebek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:bacteria (other)· 3 Research Focus:cell signaling & trafficking· 3 Organism:virus· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. B. Dalia· 6 shared N. Biais· 3 shared T. N. Dalia· 3 shared A. S. Ratkiewicz· 1 shared B. E. Herrin· 1 shared C. K. Ellison· 1 shared E. Couser· 1 shared G. Panis· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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6 shared papersMicrobiology

A. B. Dalia

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6 papers

Recent·Most cited

Retraction ATPase motors from three orthologous type IVa pilus systems support promiscuous retraction of the Vibrio cholerae competence pilus

E. Couser, J. L. Chlebek, A. B. Dalia

The paper shows that retraction ATPases from three T4aP systems can functionally replace the V. cholerae competence pilus retraction motor, while extension ATPases cannot.

bioRxiv · Oct 23, 2021Microbiology

Fresh extension of Vibrio cholerae competence type IV pili predisposes them for motor-independent retraction

J. L. Chlebek, T. N. Dalia, N. Biais, A. B. Dalia

This study investigates motor-independent retraction of Vibrio cholerae competence type IV pili and finds that freshly extended pili can retract without a retraction motor, but static pili can later retract via motor-dependent mechanisms.

bioRxiv · Mar 9, 2021Microbiology

Type IV pili share a conserved mechanism of motor-independent retraction that is an inherent property of the pilus filament

J. L. Chlebek, L. Craig, A. B. Dalia

The paper identifies a conserved mechanism for motor-independent pilus retraction in Type IV pili, showing that filament instability, not a dedicated motor, drives retraction.

bioRxiv · Feb 10, 2021 · PreprintMicrobiology

A modular chromosomally integrated toolkit for ectopic gene expression in Vibrio cholerae

T. N. Dalia, J. L. Chlebek, A. B. Dalia

This paper develops a modular chromosomally integrated toolkit for ectopic gene expression in Vibrio cholerae, showing that PBAD-riboswitch provides the tightest induction with no detectable leakiness.

bioRxiv · Mar 2, 2020Microbiology

PilT and PilU are homohexameric ATPases that coordinate to retract type IVa pili

J. L. Chlebek, H. Q. Hughes, A. S. Ratkiewicz, R. Rayyan, J. C.-Y. Wang, B. E. Herrin, T. N. Dalia, N. Biais, A. B. Dalia

This paper identifies PilU as a PilT-dependent retraction ATPase that works with PilT to retract type IVa pili in Vibrio cholerae and Acinetobacter baylyi.

PLOS Genetics · Oct 18, 2019Peer-reviewedMicrobiology

A bifunctional ATPase drives tad pilus extension and retraction

C. K. Ellison, J. Kan, J. L. Chlebek, K. R. Hummels, G. Panis, P. H. Viollier, N. Biais, A. B. Dalia, Y. Brun

This study identifies a bifunctional ATPase, CpaF, that drives both extension and retraction of tad pili in Caulobacter crescentus through ATP hydrolysis.

bioRxiv · Apr 24, 2019Microbiology