Author

H. Q. Hughes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. B. Dalia· 3 shared T. N. Dalia· 3 shared A. S. Ratkiewicz· 1 shared B. E. Herrin· 1 shared C. K. Ellison· 1 shared D. B. Rusch· 1 shared D. T. Kysela· 1 shared E. M. Boon· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersMicrobiology

A. B. Dalia

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintMay 31, 2022

The PilT retraction ATPase promotes both extension and retraction of the MSHA type IVa pilus in Vibrio cholerae

H. Q. Hughes, N. D. Christman, T. N. Dalia…·A. B. Dalia

This study shows that PilT promotes both extension and retraction of MSHA type IVa pili in Vibrio cholerae, challenging the conventional understanding of T4aP dynamics.

DOI 10.1101/2022.05.31.494186

bacteria (other)genetic perturbation / CRISPR

MicrobiologybioRxivApr 20, 2021

Oxygen depletion and nitric oxide stimulate type IV MSHA pilus retraction in Vibrio cholerae via activation of the phosphodiesterase CdpA

H. Q. Hughes, K. A. Floyd, S. Hossain…·A. B. Dalia

This study identifies oxygen depletion and nitric oxide as stimuli that trigger MSHA pilus retraction in V. cholerae via the phosphodiesterase CdpA.

DOI 10.1073/pnas.2108349119

bacteria (other)experimental assay

MicrobiologyPLOS GeneticsPeer-reviewedOct 18, 2019

PilT and PilU are homohexameric ATPases that coordinate to retract type IVa pili

J. L. Chlebek, H. Q. Hughes, A. S. Ratkiewicz…·A. B. Dalia

This paper identifies PilU as a PilT-dependent retraction ATPase that works with PilT to retract type IVa pili in Vibrio cholerae and Acinetobacter baylyi.

DOI 10.1371/journal.pgen.1008448

bacteria (other)experimental assay