Author

J. L. Reis-Cunha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:DNA methylation· 1 Research Focus:fine-mapping· 1 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

C. A. Grace· 2 shared D. C. Jeffares· 2 shared C. d. M. Pedrozo e Silva de Azevedo· 1 shared C. H. N. Costa· 1 shared D. L. Costa· 1 shared D. Speed· 1 shared J. Mottram· 1 shared K. S. Sousa Carvalho· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersEvolutionary Biology

C. A. Grace

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2 papers

Recent·Most cited

Evolutionary BiologybioRxivPreprintAug 17, 2022

Strong effects of parasite genotype on drug susceptibility in the Indian subcontinent

C. A. Grace, J. L. Reis-Cunha, D. C. Jeffares

The paper assesses the contribution of parasite genotype to drug resistance in Leishmania donovani using heritability and GWAS analyses, finding SNP/indel associations with SSG resistance and copy number variants with MIL resistance.

DOI 10.1101/2022.08.17.504263

humanDNA methylation

Evolutionary BiologybioRxivJul 28, 2022

Parasite genotype is a major predictor of mortality from visceral leishmaniasis

C. A. Grace, K. S. Sousa Carvalho, M. I. Sousa Lima…·C. H. N. Costa

This study identifies parasite genotype as a major predictor of mortality from visceral leishmaniasis in Brazil, with heritability estimates up to 83% for mortality.

DOI 10.1128/mbio.02068-22

statistical modelhost-pathogen & immune response