Author

J. Linares

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Ruiz-Villalba· 1 shared A. Sottoriva· 1 shared A.-M. Baker· 1 shared B. Pelacho· 1 shared B. Werner· 1 shared C. Barreda· 1 shared C. D. Steele· 1 shared C. Jin· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Ruiz-Villalba

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2 papers

Recent·Most cited

In vivo generation of heart and vascular system by blastocyst complementation

G. Coppiello, P. Barlabe, M. Moya-Jodar, G. Abizanda, C. Barreda, E. Iglesias, J. Linares, E. Arellano-Viera, A. Ruiz-Villalba, E. Larequi, X. Carvajal-Vergara, B. Pelacho, F. Prosper, X. L. Aranguren

This study generates transplantable hearts and vascular systems in mice using blastocyst complementation with exogenous cells, achieving viable organs with normal function and no rejection signs.

bioRxiv · Oct 4, 2022Cell Biology

Mutation Rate Evolution Drives Immune Escape In Mismatch Repair-Deficient Cancer

H. Kayhanian, P. Barmpoutis, E. Lakatos, W. C. H. Cross, G. Caravagna, L. Zapata, K. Litchfield, C. D. Steele, W. Waddingham, D. Patel, S. Milite, C. Jin, A.-M. Baker, C. Ross, D. Alexander, , M. Jansen

The paper shows that mutation rate adaptation in MMRd cancers drives immune escape by modulating neoantigen diversity and subclonal mutation rates.

bioRxiv · Mar 6, 2022 · PreprintCancer Biology