Author

J. M. Keegstra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

R. Stocker· 2 shared A. K. M. Stubbusch· 1 shared C. Magnabosco· 1 shared E. E. Clerc· 1 shared E. Frazzoli· 1 shared F. Avgidis· 1 shared F. Menolascina· 1 shared G. G. D'Souza· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

R. Stocker

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Polysaccharide breakdown products drive degradation-dispersal cycles of foraging bacteria through changes in metabolism and motility

A. K. M. Stubbusch, J. M. Keegstra, J. Schwartzman, S. Pontrelli, E. E. Clerc, S. Charlton, R. Stocker, C. Magnabosco, O. T. Schubert, M. Ackermann, G. G. D'Souza

This study shows that marine bacteria switch from polysaccharide degradation to motility when exposed to breakdown products, enabling dispersal to new nutrient sources.

bioRxiv · Jul 14, 2023Microbiology

Near-critical tuning of cooperativity revealed by spontaneous switching in a protein signalling array

J. M. Keegstra, F. Avgidis, Y. Mulla, J. S. Parkinson, T. S. Shimizu

In vivo FRET measurements of Escherichia coli chemosensory array fluctuations reveal an allosteric system poised near criticality.

bioRxiv · Dec 4, 2022Biophysics

Bacterial chemotaxis to saccharides is governed by a trade-off between sensing and uptake

N. Norris, U. Alcolombri, J. M. Keegstra, Y. Yawata, F. Menolascina, E. Frazzoli, N. M. Levine, V. I. Fernandez, R. Stocker

This paper shows E. coli limits maltose uptake via porins to enhance chemotactic sensitivity to micromolar maltose gradients despite having a high-affinity transport system.

bioRxiv · Nov 5, 2021Microbiology