STAT3 and GR cooperate to drive basal-like triple negative breast cancer gene expression and proliferation.
M. E. Conway, J. M. McDaniel, J. M. Graham, K. P. Guillen, P. G. Oliver, S. L. Parker, P. Yue, J. Turkson, D. J. Buchsbaum, B. E. Welm, R. M. Myers, K. E. Varley
This study identifies GR and STAT3 as cooperative drivers of basal-like triple negative breast cancer gene expression and shows that their inhibition synergistically reduces cell proliferation.
bioRxiv · Aug 9, 2019Cancer Biology