Author

M. E. Conway

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

K. E. Varley· 2 shared A. A. Cluntun· 1 shared B. E. Welm· 1 shared B. R. Wilde· 1 shared B. Wang· 1 shared D. E. Ayer· 1 shared D. J. Buchsbaum· 1 shared I. George· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

K. E. Varley

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Author profile →

3 papers

Recent·Most cited

TXNIP loss expands Myc-dependent transcriptional programs by increasing Myc genomic binding

T.-Y. Lim, B. R. Wilde, M. L. Thomas, K. E. Murphy, J. M. Vahrenkamp, M. E. Conway, K. E. Varley, J. Gertz, D. E. Ayer

This study shows that TXNIP loss increases Myc genomic binding, expanding Myc-dependent transcriptional programs without increasing Myc levels or activity.

bioRxiv · Aug 4, 2022 · PreprintCancer Biology

Network-aware reaction pattern recognition reveals regulatory signatures of mitochondrial dysfunction

J. A. Berg, Y. Zhou, Y. Ouyang, T. C. Waller, A. A. Cluntun, M. E. Conway, S. M. Nowinski, T. Van Ry, I. George, J. E. Cox, B. Wang, J. Rutter

The paper introduces Metaboverse, a tool for network-aware reaction pattern recognition in metabolic data, identifying regulatory signatures of mitochondrial dysfunction in lung adenocarcinoma and respiratory deficiency models.

bioRxiv · Jun 25, 2020 · PreprintBiochemistry

STAT3 and GR cooperate to drive basal-like triple negative breast cancer gene expression and proliferation.

M. E. Conway, J. M. McDaniel, J. M. Graham, K. P. Guillen, P. G. Oliver, S. L. Parker, P. Yue, J. Turkson, D. J. Buchsbaum, B. E. Welm, R. M. Myers, K. E. Varley

This study identifies GR and STAT3 as cooperative drivers of basal-like triple negative breast cancer gene expression and shows that their inhibition synergistically reduces cell proliferation.

bioRxiv · Aug 9, 2019Cancer Biology