Author

D. J. Buchsbaum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. B. Keeton· 1 shared A. B. Ward· 1 shared A. Chakraborty· 1 shared A. K. Mitra· 1 shared B. E. Welm· 1 shared B. F. El-Rayes· 1 shared B. Shin· 1 shared C. A. Klug· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. B. Keeton

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Author profile →

3 papers

Recent·Most cited

A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer

J. Foote, T. E. Mattox, A. B. Keeton, X. Chen, F. T. Smith, K. L. Berry, T. W. Holmes, J. Wang, C.-H. Wang, A. B. Ward, A. K. Mitra, V. R. Alcantara, C. Hardy, K. G. Fleten, K. Flatmark, , G. A. Piazza

This paper introduces ADT-007, a novel pan-RAS inhibitor that effectively blocks tumor growth in mouse models of GI cancer by targeting RAS activation and inducing apoptosis.

bioRxiv · May 17, 2023 · PreprintCancer Biology

ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression

A. Chakraborty, N. Bhalerao, M. P. Marciel, J. Hwang, C. Britain, E. E. Eltoum, R. B. Jones, K. L. Alexander, L. E. Smythies, P. D. Smith, D. K. Crossman, M. R. Crowley, B. Shin, L. E. Harrington, Z. Yan, , S. L. Bellis

This study identifies ST6GAL1 sialyltransferase as a promoter of acinar-to-ductal metaplasia and pancreatic cancer progression through glycosylation-dependent mechanisms.

bioRxiv · Apr 28, 2022 · PreprintCancer Biology

STAT3 and GR cooperate to drive basal-like triple negative breast cancer gene expression and proliferation.

M. E. Conway, J. M. McDaniel, J. M. Graham, K. P. Guillen, P. G. Oliver, S. L. Parker, P. Yue, J. Turkson, D. J. Buchsbaum, B. E. Welm, R. M. Myers, K. E. Varley

This study identifies GR and STAT3 as cooperative drivers of basal-like triple negative breast cancer gene expression and shows that their inhibition synergistically reduces cell proliferation.

bioRxiv · Aug 9, 2019Cancer Biology