ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes
F. Shi, J. M. Mendrola, J. B. Sheetz, N. Wu, A. Sommer, K. F. Speer, J. N. Noordermeer, Z.-Y. Kan, K. Perry, S. W. Englander, S. E. Stayrook, L. G. Fradkin, M. A. Lemmon
The paper presents crystal structures of Drosophila ROR and RYK orthologs, revealing distinct WNT-recognition mechanisms through their extracellular domains.
bioRxiv · Apr 29, 2021Biochemistry