Author

S. E. Stayrook

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Drosophila· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

M. A. Lemmon· 2 shared A. Kiyatkin· 1 shared A. Sommer· 1 shared C. A. Leche· 1 shared C. Hu· 1 shared F. Shi· 1 shared J. B. Sheetz· 1 shared J. M. Mendrola· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

M. A. Lemmon

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 4, 2021

Glioblastoma mutations impair ligand discrimination by EGFR

C. Hu, C. A. Leche, A. Kiyatkin…·M. A. Lemmon

This study shows that GBM mutations in EGFR disrupt ligand discrimination by altering dimer structure and stability, leading to aberrant signaling.

DOI 10.1101/2021.05.04.442654

humanprotein structure

𝕏 PostBluesky

BiochemistrybioRxivApr 29, 2021

ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes

F. Shi, J. M. Mendrola, J. B. Sheetz…·M. A. Lemmon

The paper presents crystal structures of Drosophila ROR and RYK orthologs, revealing distinct WNT-recognition mechanisms through their extracellular domains.

DOI 10.1016/j.celrep.2021.109834

Drosophilastructural biology

𝕏 PostBluesky