Cell BiologybioRxiv
Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness Versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis
J. M. SanMiguel, E. Eudy, M. A. Loberg…·J. J. Trowbridge
The paper investigates how distinct TNF receptors influence mutant HSC fitness and lineage output in Dnmt3a-mutant clonal hematopoiesis, showing independent regulation of clone size and cell type production.
DOI 10.1158/2159-8290.cd-22-0086