Author

J. Mark

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Ecology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:ecology & biodiversity· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Arnell· 1 shared A. Casella· 1 shared A. N. H. Khan· 1 shared A. R. McGray· 1 shared A. van Soesbergen· 1 shared B. A. Davidson· 1 shared B. D. Litchy· 1 shared B. E. Baysal· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperEcology

A. Arnell

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ASO-mediated knockdown of GPNMB in mutant-GRN and Grn-deficient peripheral myeloid cells disrupts lysosomal function and immune responses

R. Wallings, D. A. Gillett, H. Staley, S. Mahn, J. Mark, N. Neighbarger, H. kordasiewicz, W. D. Hirst, M. G. Tansey

This study shows that reducing GPNMB in progranulin-deficient myeloid cells impairs lysosomal function and immune responses, suggesting GPNMB is essential for maintaining immune homeostasis.

bioRxiv · Jul 22, 2024 · PreprintImmunology

High dose dietary vitamin D allocates surplus calories to muscle and growth instead of fat via modulation of myostatin and leptin signaling.

C. Long, Z. Tara, A. Casella, J. Mark, J. Roizen

This paper shows high-dose vitamin D reduces myostatin and increases leptin production and sensitivity, directing excess calories to muscle and growth rather than fat.

bioRxiv · May 19, 2022 · PreprintPhysiology

Areas of global importance for terrestrial biodiversity, carbon, and water

M. Jung, A. Arnell, X. De Lamo, S. Garcia-Rangel, M. Lewis, J. Mark, C. Merow, L. Miles, I. Ondo, S. Pironon, C. Ravilious, M. Rivers, D. Schepashenko, O. Tallowin, A. van Soesbergen, , Wieringa

The paper identifies global terrestrial areas prioritized for conservation to maximize synergies between biodiversity, carbon retention, and water provisioning.

bioRxiv · Apr 16, 2020Ecology

RNA editing enzyme APOBEC3A promotes pro-inflammatory (M1) macrophage polarization

E. Y. Alqassim, S. Sharma, A. N. H. Khan, T. Emmons, E. Cortes-Gomez, K. Singel, J. Mark, B. A. Davidson, A. R. McGray, Q. Liu, B. D. Litchy, K. Moysich, J. Wang, K. Odunsi, B. H. Segal, B. E. Baysal

This study shows APOBEC3A promotes M1 macrophage polarization through RNA editing, affecting gene expression and cytokine secretion.

bioRxiv · Mar 20, 2020Immunology