Author

J. Metcalf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Ecology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. D. Augustine· 1 shared A. Hoch· 1 shared A. Konstorum· 1 shared A. Ozonoff· 1 shared B. Grenfell· 1 shared B. N. Gray· 1 shared B. Pulendran· 1 shared C. B. Cairns· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. D. Augustine

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A unified theory for predicting pathogen mutual invasibility and co-circulation

S. W. Park, S. Cobey, J. Metcalf, J. Levine, B. Grenfell

This paper develops a framework to predict pathogen mutual invasibility and co-circulation using ecological theory, finding near-universal mutual invasibility across major pathogen systems.

bioRxiv · Apr 22, 2024 · PreprintEcology

Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants

J. P. Gygi, C. Maguire, R. K. Patel, P. Shinde, A. Konstorum, C. P. Shannon, L. Xu, A. Hoch, N. Jayavelu, IMPACC Network, E. K. Haddad, E. F. Reed, M. Kraft, G. A. McComsey, J. Metcalf, , Pete

This study identifies immune programs linked to COVID-19 severity and mortality through longitudinal multi-omics analysis of 1,152 hospitalized patients.

bioRxiv · Nov 3, 2023Immunology

Cas12a2 elicits abortive infection via RNA-triggered destruction of double-stranded DNA

O. Dmytrenko, G. Neumann, T. Hallmark, D. J. Keiser, V. M. Crowley, E. Vialetto, I. Mougiakos, K. G. Wandera, H. Domgaard, J. Weber, J. Metcalf, M. B. Begemann, B. N. Gray, R. N. Jackson, C. L. Beisel

This study shows that Cas12a2 causes abortive infection by degrading double-stranded DNA through RNA-triggered activity, and demonstrates its use as an RNA detection tool.

bioRxiv · Jun 13, 2022 · PreprintMicrobiology