Author

O. Dmytrenko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

K. J. Lavine· 2 shared M. S. Diamond· 2 shared A. Bredemeyer· 1 shared A. Carfi· 1 shared A. Khakimzhan· 1 shared A. Kovacs· 1 shared A. L. Bailey· 1 shared A. L. Bredemeyer· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

K. J. Lavine

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Author profile →

5 papers

Recent·Most cited

Cell-free expression with a quartz crystal microbalance enables rapid, dynamic, and label-free characterization of membrane-interacting proteins

A. Khakimzhan, Z. Izri, S. Thompson, O. Dmytrenko, P. Fischer, C. Beisel, V. Noireaux

The paper introduces TXTL-QCMD, a method to dynamically characterize membrane-interacting proteins without purification or labeling, revealing insights into IIMP-membrane interactions.

bioRxiv · Jan 14, 2024Biophysics

Cas12a2 elicits abortive infection via RNA-triggered destruction of double-stranded DNA

O. Dmytrenko, G. Neumann, T. Hallmark, D. J. Keiser, V. M. Crowley, E. Vialetto, I. Mougiakos, K. G. Wandera, H. Domgaard, J. Weber, J. Metcalf, M. B. Begemann, B. N. Gray, R. N. Jackson, C. L. Beisel

This study shows that Cas12a2 causes abortive infection by degrading double-stranded DNA through RNA-triggered activity, and demonstrates its use as an RNA detection tool.

bioRxiv · Jun 13, 2022 · PreprintMicrobiology

Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice

B. Ying, S. M. Scheaffer, B. Whitener, C.-Y. Liang, O. Dmytrenko, S. Mackin, K. Wu, D. Lee, L. E. Avena, Z. Chong, J. B. Case, L. Ma, T. Kim, C. Sein, A. Woods, , M. S. Diamond

This study shows that boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibodies and protection against B.1.1.529 in mice, with the Omicron-matched booster showing slightly better outcomes.

bioRxiv · Feb 7, 2022 · PreprintMicrobiology

Resident Cardiac Macrophages Mediate Adaptive Myocardial Remodeling

N. R. Wong, J. Mohan, B. Kopecky, S. Guo, L. Du, J. Leid, O. Dmytrenko, H. Luehmann, G. Bajpai, L. Ewald, L. Bell, N. Patel, I. Lokshina, A. Bredemeyer, C. J. Weinheimer, , K. J. Lavine

This study identifies CCR2- resident cardiac macrophages as critical for adaptive myocardial remodeling in heart failure, showing their role in ventricular remodeling and coronary angiogenesis.

bioRxiv · Jan 28, 2021Immunology

SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis

A. L. Bailey, O. Dmytrenko, L. Greenberg, A. L. Bredemeyer, P. Ma, J. Liu, V. Penna, L. Lai, E. S. Winkler, S. Sviben, E. Brooks, A. P. Nair, K. A. Heck, A. S. Rali, L. Simpson, , K. J. Lavine

This study shows SARS-CoV-2 infects human engineered heart tissues, causing myocarditis-like features, and identifies ACE2 and proteases as entry factors.

bioRxiv · Nov 4, 2020Immunology