MicrobiologybioRxiv
Single Cell Variability of CRISPR-Cas Interference and Adaptation
R. E. McKenzie, E. M. Keizer, J. N. A. Vink…·S. J. J. Brouns
The paper studies CRISPR-Cas interference and adaptation in E. coli, finding cell-to-cell variability in clearance times due to primed adaptation, with Cascade binding as the main source of heterogeneity.
DOI 10.15252/msb.202110680