The Amot/Integrin protein complex transmits mechanical forces required for vascular expansion
Y. Zhang, Y. Zhang, S. Kameishi, G. Barutello, Y. Zheng, N. P. Tobin, J. Nicosia, K. Hennig, D. K.-C. Chiu, M. Balland, T. H. Barker, F. Cavallo, L. Holmgren
This study shows that Amot is essential for vascular expansion by transmitting mechanical forces through the integrin adhesome in mice.
bioRxiv · Jan 14, 2021Cell Biology