NLRP3 inflammasome inhibition rescues Hutchinson-Gilford Progeria cellular phenotype and extend longevity of an animal model
E. Alcocer-Gomez, B. Castejon-Vega, J. Nunez-Vasco, D. Lendines-Cordero, J. M. Navarro-Pando, M. D. Cordero
This study shows that inhibiting the NLRP3 inflammasome improves cellular phenotype and extends lifespan in HGPS animal models.
bioRxiv · Sep 9, 2020 · PreprintImmunology