Author

J. O. McInerney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 6 Research Focus:chromatin & epigenetic regulation· 4 Research Focus:gene regulatory network inference· 3 Organism:bacteria (other)· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

F. J. Whelan· 4 shared M. Rusilowicz· 2 shared R. J. Hall· 2 shared A. McNally· 1 shared B. Constantinides· 1 shared C. Connor· 1 shared C. J. Creevey· 1 shared D. Newman· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersEvolutionary Biology

F. J. Whelan

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Author profile →

6 papers

Recent·Most cited

Bursts of novel composite gene families at major nodes in animal evolution

P. O. Mulhair, R. J. Moran, J. s. Pathmanathan, D. Sussfeld, C. J. Creevey, K. Siu-Ting, F. J. Whelan, D. Pisani, B. Constantinides, E. Pelletier, p. lopez, E. Bapteste, J. O. McInerney, M. J. O'Connell

The paper identifies composite gene families in animals, showing they emerge abruptly at major evolutionary nodes and are independently evolved in multiple clades.

bioRxiv · Jul 10, 2023 · PreprintEvolutionary Biology

High Frequency of Dynamic Rearrangements in CRISPR Loci

Y. Ou, J. O. McInerney

This study identifies frequent dynamic rearrangements in CRISPR loci across prokaryotic genomes, challenging the idea that spacer order reflects infection timing.

bioRxiv · May 19, 2022 · PreprintEvolutionary Biology

Gene-gene relationships in an Escherichia coli accessory genome are linked to function and mobility

R. J. Hall, F. J. Whelan, E. A. Cummins, C. Connor, A. McNally, J. O. McInerney

This study identifies gene-gene relationships in an Escherichia coli accessory genome, showing that co-occurrence is driven by function and mobility.

bioRxiv · Mar 26, 2021Evolutionary Biology

Evidence for selection in a prokaryote pangenome

F. J. Whelan, R. J. Hall, J. O. McInerney

The paper analyzes Pseudomonas genomes to show that accessory genes are structured by selection, forming interacting gene sets that function together in strains.

bioRxiv · Oct 28, 2020 · PreprintMicrobiology

Coinfinder: Detecting Significant Associations and Dissociations in Pangenomes

F. J. Whelan, M. Rusilowicz, J. O. McInerney

Coinfinder identifies gene associations and dissociations in pangenomes by analyzing their phylogenetic distribution across gene families.

bioRxiv · Nov 29, 2019Microbiology

Reconstructing and Analysing The Genome of The Last Eukaryote Common Ancestor to Better Understand the Transition from FECA to LECA.

D. Newman, F. Whelan, M. Moore, M. Rusilowicz, J. O. McInerney

This study reconstructs the LECA genome using modern eukaryotic genomes and identifies key gene gains and functional changes during the FECA-to-LECA transition.

bioRxiv · Feb 1, 2019 · PreprintEvolutionary Biology