R. J. Hall

Multidrug resistance plasmids commonly reprogramme expression of metabolic genes in Escherichia coli

This study introduces eight MDR plasmids into E. coli and shows varying transcriptional impacts and fitness costs, with metabolic genes frequently affected.

Non-antibiotic pharmaceuticals exhibit toxicity against Escherichia coli at environmentallyrelevant concentrations with no evolution of cross-resistance to antibiotics

This study shows non-antibiotic pharmaceuticals inhibit E. coli growth at environmental concentrations without promoting cross-resistance to antibiotics.

Growth in a biofilm promotes conjugation of a blaNDM-1-bearing plasmid between Klebsiella pneumoniae strains

This study shows biofilm growth significantly increases conjugative transfer of a carbapenem resistance plasmid in K. pneumoniae without fitness costs.

Effects of Food Supplementation and Helminth Removal on Space Use and Spatial Overlap in Wild Rodent Populations

This study examines how food supplementation and helminth removal affect space use and spatial overlap in bank voles, finding that food reduces space use while helminth removal increases it, with seasonal and demographic variations.

Pangenome evolution in Escherichia coli is sequence type, not phylogroup, specific

The paper compares pangenomes of different Escherichia coli sequence types to show that pangenome evolution is influenced by sequence type-specific factors rather than phylogroup relationships.

Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins

The paper identifies the structural basis of the interaction between SNX17 and PDLIM family proteins, revealing a specific PDZ binding motif and unique electrostatic contacts.

Gene-gene relationships in an Escherichia coli accessory genome are linked to function and mobility

This study identifies gene-gene relationships in an Escherichia coli accessory genome, showing that co-occurrence is driven by function and mobility.

De novo macrocyclic peptides for inhibiting, stabilising and probing the function of the Retromer endosomal trafficking complex

The paper develops macrocyclic peptides that inhibit, stabilize, and probe the Retromer complex's function, showing high affinity and specificity for different subunits.

Evidence for selection in a prokaryote pangenome

The paper analyzes Pseudomonas genomes to show that accessory genes are structured by selection, forming interacting gene sets that function together in strains.

Reactivation of latent infections with migration shapes population-level disease dynamics

This study develops a mechanistic model showing how migratory relapse affects disease dynamics in migratory hosts, finding that relapse timing can increase or decrease infection prevalence depending on pathogen and host traits.

Light pollution affects West Nile virus exposure risk across Florida.

This study finds light pollution, specifically artificial light at night, is a stronger predictor of West Nile virus exposure risk in Florida than urbanization or temperature.

Simulating the evolutionary trajectories of metabolic pathways for insect symbionts in the Sodalis genus

The paper uses metabolic modeling and evolutionary algorithms to simulate the evolutionary trajectories of Sodalis glossinidius after internalization, showing gene loss impacts on evolved populations.

Mosquito species and age influence thermal performance of traits relevant to malaria transmission

This study compares temperature-dependent transmission models using daily trait values versus lifetime trait values in Anopheles stephensi, showing differences in temperature suitability for malaria transmission.

Light Pollution Increases West Nile Virus Competence in a Ubiquitous Passerine Reservoir Species

This study shows that dim light at night increases the infectiousness of house sparrows to West Nile virus, potentially raising outbreak risk by 41%.