Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets
M. P. Vincent, S. Bobbala, N. B. Karabin, M. Frey, Y. Liu, J. O. Navidzadeh, T. Stack, E. A. Scott
This study shows that nanocarrier surface chemistry can stabilize or denature adsorbed albumin, affecting macrophage clearance through SR-A1 receptor recognition.
bioRxiv · Apr 24, 2020Bioengineering