Author

M. Frey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

E. A. Scott· 4 shared S. Bobbala· 4 shared M. Vincent· 2 shared N. B. Karabin· 2 shared S. Allen· 2 shared T. Stack· 2 shared A. Groves· 1 shared A. Iqbal· 1 shared

Activity by Year

2018-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersBioengineering

E. A. Scott

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

CellSeg3D: self-supervised 3D cell segmentation for fluorescence microscopy

C. Achard, T. Kousi, M. Frey, M. Vidal, Y. Paychere, C. Hofmann, A. Iqbal, S. B. Hausmann, S. Pages, M. W. Mathis

CellSeg3D introduces self-supervised 3D cell segmentation models for fluorescence microscopy, achieving performance comparable to supervised methods without requiring ground truth labels.

bioRxiv · May 17, 2024Cell Biology

Subcutaneous nanotherapy repurposes the immunosuppressive mechanism of rapamycin to enhance allogeneic islet graft viability

J. Burke, X. Zhang, S. Bobbala, M. Frey, C. Fuentes, H. Haddad, S. Allen, R. Richardson, G. Ameer, E. A. Scott

This paper shows subcutaneous rapamycin delivery via nanocarriers changes its immunosuppressive mechanism, improving islet graft survival in a transplant model.

bioRxiv · Sep 3, 2020Bioengineering

The Combination of Morphology and Surface Chemistry Defines the Biological Identity of Nanocarriers in Human Blood

E. A. Scott, N. B. Karabin, M. Vincent, S. Allen, S. Bobbala, M. Frey, S. Yi, Y. Yang

The paper shows that both the surface chemistry and morphology of nanocarriers influence their protein corona composition and immune interactions in human blood.

bioRxiv · Sep 2, 2020Bioengineering

Co-administration of macropinocytosis inhibitory nanoparticles (MiNP) for enhanced nanoparticle circulation time and target tissue accumulation following subcutaneous injection

T. Stack, Y.-G. Liu, M. Frey, S. Bobbala, M. Vincent, E. A. Scott

This paper shows that co-injecting macropinocytosis inhibitory nanoparticles (MiNP) with targeted nanoparticles improves their circulation time and tissue accumulation after subcutaneous injection.

bioRxiv · Aug 26, 2020Bioengineering

Surface chemistry-mediated modulation of adsorbed albumin folding state specifies nanocarrier clearance by distinct macrophage subsets

M. P. Vincent, S. Bobbala, N. B. Karabin, M. Frey, Y. Liu, J. O. Navidzadeh, T. Stack, E. A. Scott

This study shows that nanocarrier surface chemistry can stabilize or denature adsorbed albumin, affecting macrophage clearance through SR-A1 receptor recognition.

bioRxiv · Apr 24, 2020Bioengineering

Gfi1-expressing Paneth cells revert to stem cells following intestinal injury

M.-S. Chen, Y.-H. Lo, J. Butkus, W. Zou, Y.-J. Tseng, H.-I. Jen, S. Patel, A. Groves, M. Estes, E. Sahin, M. Frey, P. Dempsey, N. Shroyer

This study shows that Gfi1-expressing secretory cells can revert to stem cells after intestinal injury, with PI3kinase/AKT and WNT signaling enhancing this process.

bioRxiv · Jul 16, 2018 · PreprintCell Biology