Author

J. O. Szablowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Assay:protein sequence· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

J. P. Seo· 2 shared J. S. Trippett· 2 shared S. Nouraein· 2 shared Z. Huang· 2 shared A. Mitrofan· 1 shared C. Horak· 1 shared H. C. Del Mundo· 1 shared H. Li· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioengineering

J. P. Seo

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Author profile →

4 papers

Recent·Most cited

Engineering Regionally-Activated Drugs for Neuroscience

Z. Huang, A. Mitrofan, S. Nouraein, C. Horak, J. P. Seo, M. Harb, R. Jin, J. O. Szablowski

This paper introduces RAID, a noninvasive method to control specific brain cell types using ultrasound and enzyme-prodrug pairs for sustained neuromodulation.

bioRxiv · Oct 12, 2023 · PreprintBioengineering

Acoustically-Targeted Measurement of Transgene Expression in the Brain

J. P. Seo, J. S. Trippett, Z. Huang, R. Wang, S. Lee, J. O. Szablowski

This paper introduces REMIS, a noninvasive method to measure gene expression in the brain using ultrasound and blood tests, and demonstrates its effectiveness in monitoring chemogenetic activity.

bioRxiv · May 23, 2023 · PreprintBioengineering

Acoustically Targeted Noninvasive Gene Therapy in Large Brain Regions

S. Nouraein, V. A. Saenz, H. C. Del Mundo, J. Yiu, J. O. Szablowski

This study evaluates the efficiency and safety of using focused ultrasound to deliver gene therapy to large brain regions, finding high transduction efficiency and safety but some neuron loss.

bioRxiv · Jan 19, 2023 · PreprintBioengineering

Engineering Viral Vectors for Acoustically Targeted Gene Delivery

H. Li, J. E. Heath, J. S. Trippett, M. G. Shapiro, J. O. Szablowski

This study engineers AAV vectors for acoustically targeted gene delivery, improving specificity and efficiency while reducing peripheral transduction.

bioRxiv · Jul 26, 2021Bioengineering