TROP2 represents a negative prognostic factor in colorectal adenocarcinoma and its expression is associated with features of epithelial-mesenchymal transition and invasiveness
J. Svec, M. Stastna, L. Janeckova, D. Hrckulak, M. Vojtechova, J. Onhajzer, V. Kriz, K. Galuskova, E. Sloncova, J. Kubovciak, L. Pfeiferova, J. Hrudka, R. Matej, P. Waldauf, L. Havluj, , V. Korinek
This study shows TROP2 is a negative prognostic factor in colorectal cancer, linked to metastasis and poor differentiation, and suggests it could be a therapeutic target.
bioRxiv · Jul 27, 2022Cancer Biology