Author

J. Kubovciak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. Hrckulak· 2 shared M. Kolar· 2 shared M. Stastna· 2 shared M. Vojtechova· 2 shared V. Korinek· 2 shared A. Drobek· 1 shared A. Markos· 1 shared A. Moudra· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

D. Hrckulak

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell type and regulatory analysis in amphioxus illuminates evolutionary origin of the vertebrate head

A. Markos, J. Kubovciak, S. Mikula Mrstakova, J. Paces, A. Zitova, Z. Kozmik, S. Machacova, Z. Kozmik, I. Kozmikova

The paper identifies vertebrate head-related cell populations in amphioxus, a close relative of the chordate ancestor, through single-cell transcriptomics and functional analysis.

bioRxiv · Jan 18, 2024Evolutionary Biology

Terminal differentiation of villus-tip enterocytes is governed by distinct members of Tgfβ superfamily

L. Berkova, H. Fazilaty, Q. Yang, J. Kubovciak, M. Stastna, D. Hrckulak, M. Vojtechova, M. D. Brugger, G. Hausmann, P. Liberali, V. Korinek, K. Basler, T. Valenta

This study identifies distinct roles of Bmp2 and Tgfβ in driving specific enterocytic programs at different villus regions, with Bmp2 promoting terminal differentiation at the villus-tip.

bioRxiv · Nov 11, 2022Cell Biology

TROP2 represents a negative prognostic factor in colorectal adenocarcinoma and its expression is associated with features of epithelial-mesenchymal transition and invasiveness

J. Svec, M. Stastna, L. Janeckova, D. Hrckulak, M. Vojtechova, J. Onhajzer, V. Kriz, K. Galuskova, E. Sloncova, J. Kubovciak, L. Pfeiferova, J. Hrudka, R. Matej, P. Waldauf, L. Havluj, , V. Korinek

This study shows TROP2 is a negative prognostic factor in colorectal cancer, linked to metastasis and poor differentiation, and suggests it could be a therapeutic target.

bioRxiv · Jul 27, 2022Cancer Biology

Phenotypic and clonal stability of antigen-inexperienced memory-like T cells across the genetic background, hygienic status, and aging

A. Moudra, V. Niederlova, J. Novotny, L. Schmiedova, J. Kubovciak, T. Matejkova, A. Drobek, M. Pribikova, R. Stopkova, D. Cizkova, A. Neuwirth, J. Michalik, K. Krizova, T. Hudcovic, M. Kolar, , O. Stepanek

This study characterizes antigen-inexperienced memory-like T cells across genetic backgrounds, hygienic conditions, and aging, showing their clonal stability and distinct subsets defined by CD122 expression.

bioRxiv · Sep 1, 2020Immunology