Author

J. P. Natekar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

H. A. Rothan· 3 shared H. Pathak· 3 shared K. Arora· 3 shared M. Kumar· 3 shared P. Kumari· 3 shared S. Stone· 3 shared S. Sharma· 2 shared M. A. Brinton· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersMicrobiology

H. A. Rothan

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3 papers

Recent·Most cited

Differential pathogenesis of SARS-CoV-2 variants of concern in human ACE2-expressing mice

J. P. Natekar, H. Pathak, S. Stone, P. Kumari, S. Sharma, K. Arora, H. A. Rothan, M. Kumar

This study compares the pathogenesis of SARS-CoV-2 variants in human ACE2-expressing mice, finding that some variants are more lethal and replicate more in the lungs and brain.

bioRxiv · Apr 4, 2022Microbiology

SARS-CoV-2 variants of concern infect the respiratory tract and induce inflammatory response in wild-type laboratory mice

S. Stone, H. A. Rothan, J. P. Natekar, P. Kumari, S. Sharma, H. Pathak, K. Arora, T. T. Aurani, M. Kumar

This study infects wild-type mice with SARS-CoV-2 variants to show B.1.1.7 and B.1.351 replicate more efficiently and induce stronger inflammatory responses than the original B.1 virus.

bioRxiv · Sep 29, 2021Microbiology

Neuroinvasion and encephalitis following intranasal inoculation of SARS-CoV-2 in K18-hACE2 mice

P. Kumari, H. A. Rothan, J. P. Natekar, S. Stone, H. Pathak, P. G. Strate, K. Arora, M. A. Brinton, M. Kumar

This study shows that SARS-CoV-2 causes neuroinvasion and encephalitis in K18-hACE2 mice, leading to 100% mortality by day 6 post-infection.

bioRxiv · Dec 14, 2020Microbiology