Neuroinvasion and encephalitis following intranasal inoculation of SARS-CoV-2 in K18-hACE2 mice
P. Kumari, H. A. Rothan, J. P. Natekar, S. Stone, H. Pathak, P. G. Strate, K. Arora, M. A. Brinton, M. Kumar
This study shows that SARS-CoV-2 causes neuroinvasion and encephalitis in K18-hACE2 mice, leading to 100% mortality by day 6 post-infection.
bioRxiv · Dec 14, 2020Microbiology