Quantification of Microtubule Stutters: Dynamic Instability Behaviors that are Strongly Associated with Catastrophe
S. M. Mahserejian, J. P. Scripture, A. J. Mauro, E. J. Lawrence, E. M. Jonasson, K. S. Murray, J. Li, M. K. Gardner, M. Alber, M. Zanic, H. V. Goodson
The paper introduces STADIA, a tool to quantify microtubule dynamics, including stutters, and shows stutters precede catastrophes, with CLASP2{gamma} promoting their return to growth.
bioRxiv · Dec 16, 2019Cell Biology