Author

J. P. Zepecki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Fiser· 2 shared D. Karambizi· 2 shared N. Tapinos· 2 shared A. Corseri· 1 shared A. Sarkar· 1 shared C. Guetta-Terrier· 1 shared D. Lee· 1 shared E. Fajardo· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

A. Fiser

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2 papers

Recent·Most cited

Inhibition of HDAC7 reprograms the histone H3.3 landscape to induce heterochromatin spreading and DNA replication defects in cancer cells.

O. Hassan, M. Pizzagalli, O. Leary, J. P. Zepecki, A. Corseri, L. J. Wu, S. Sasipalli, D. Lee, L. Hayward, L. Tran, E. Fajardo, A. Fiser, D. Karambizi, N. Tapinos

This study shows that inhibiting HDAC7 alters H3.3 deposition and chromatin structure, leading to DNA replication defects and increased sensitivity to DNA damage in cancer cells.

bioRxiv · Mar 12, 2024Cancer Biology

miRNA-mediated loss of m6A increases nascent translation in glioblastoma

J. P. Zepecki, D. Karambizi, J. E. Fajardo, K. M. Snyder, C. Guetta-Terrier, O. Y. Tang, J.-S. Chen, A. Sarkar, A. Fiser, S. A. Toms, N. Tapinos

The paper shows that miRNA-mediated loss of m6A increases nascent translation in glioblastoma stem cells during differentiation.

bioRxiv · Aug 28, 2020Cancer Biology