Author

O. Hassan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:Drosophila· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

B. Movsas· 2 shared F. Siddiqui· 2 shared K. Adhikari· 2 shared P. J. Delclos· 2 shared R. P. Meisel· 2 shared S. L. Brown· 2 shared S. Nyati· 2 shared S. Sriramulu· 2 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

B. Movsas

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

BUB1 regulates non-homologous end joining pathway to mediate radioresistance in triple-negative breast cancer

S. Sriramulu, S. Thoidingjam, W.-M. Chen, O. Hassan, F. Siddiqui, S. L. Brown, B. Movsas, M. D. Green, A. J. Davis, C. Speers, E. Walker, S. Nyati

This study identifies BUB1 as a regulator of non-homologous end joining (NHEJ) in triple-negative breast cancer (TNBC), showing that its inhibition sensitizes TNBC cells to radiotherapy.

bioRxiv · May 7, 2024Cancer Biology

BUB1 inhibition sensitizes lung cancer cell lines to radiotherapy and chemoradiotherapy

S. Thoidingjam, S. Sriramulu, O. Hassan, S. L. Brown, F. Siddiqui, B. Movsas, S. Gadgeel, S. Nyati

This study shows BUB1 inhibition enhances the effectiveness of radiotherapy and chemoradiation in lung cancer cell lines.

bioRxiv · Apr 19, 2024 · PreprintCancer Biology

Inhibition of HDAC7 reprograms the histone H3.3 landscape to induce heterochromatin spreading and DNA replication defects in cancer cells.

O. Hassan, M. Pizzagalli, O. Leary, J. P. Zepecki, A. Corseri, L. J. Wu, S. Sasipalli, D. Lee, L. Hayward, L. Tran, E. Fajardo, A. Fiser, D. Karambizi, N. Tapinos

This study shows that inhibiting HDAC7 alters H3.3 deposition and chromatin structure, leading to DNA replication defects and increased sensitivity to DNA damage in cancer cells.

bioRxiv · Mar 12, 2024Cancer Biology

Trans regulation of an odorant binding protein by a proto-Y chromosome affects male courtship in house fly

P. J. Delclos, K. Adhikari, A. B. Mai, O. Hassan, A. A. Oderhowho, V. Sriskantharajah, T. Trinh, R. P. Meisel

The paper identifies a Y-linked gene that regulates odorant binding proteins, affecting male courtship in house flies and demonstrating a molecular mechanism for sexually antagonistic evolution.

bioRxiv · Jun 22, 2021 · PreprintEvolutionary Biology

Thermal tolerance and preference are both consistent with the clinal distribution of house fly proto-Y chromosomes

P. J. Delclos, K. Adhikari, O. Hassan, J. E. Cambric, A. G. Matuk, R. I. Presley, J. Tran, V. Sriskantharajah, R. P. Meisel

This study shows that male-determining chromosomes in house flies affect thermal tolerance and preference in a way consistent with their clinal distribution across latitudes.

bioRxiv · Jan 14, 2021Evolutionary Biology