Author

L. J. Wu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:bacteria (other)· 4 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cell signaling & trafficking· 2 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

J. Errington· 4 shared A. Anchimiuk· 1 shared A. Corseri· 1 shared A. Fiser· 1 shared A. R. Tyler· 1 shared A. S. B. Jalal· 1 shared A. Wipat· 1 shared B. Kepplinger· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

J. Errington

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Inhibition of HDAC7 reprograms the histone H3.3 landscape to induce heterochromatin spreading and DNA replication defects in cancer cells.

O. Hassan, M. Pizzagalli, O. Leary, J. P. Zepecki, A. Corseri, L. J. Wu, S. Sasipalli, D. Lee, L. Hayward, L. Tran, E. Fajardo, A. Fiser, D. Karambizi, N. Tapinos

This study shows that inhibiting HDAC7 alters H3.3 deposition and chromatin structure, leading to DNA replication defects and increased sensitivity to DNA damage in cancer cells.

bioRxiv · Mar 12, 2024Cancer Biology

Mircubactin B rescues the lethal effect of cell wall biosynthesis mutations in Bacillus subtilis.

B. Kepplinger, X. Wen, A. R. Tyler, B.-Y. Kim, J. Brown, P. Banks, Y. Dashti, E. S. Mackenzie, C. Wills, Y. Kawai, K. J. Waldron, N. E. E. Allenby, L. J. Wu, M. J. Hall, J. Errington

The paper identifies mirubactin B, a compound that rescues growth defects in Bacillus subtilis rod-complex mutants, showing activity beyond simple iron sequestration.

bioRxiv · Apr 24, 2022 · PreprintMicrobiology

Chromosome remodelling by SMC/Condensin in B. subtilis is regulated by Soj/ParA during growth and sporulation

D. M. Roberts, A. Anchimiuk, T. G. Kloosterman, H. Murray, L. J. Wu, S. Gruber, J. Errington

The paper shows that ParA/Soj proteins regulate SMC complex redistribution during axial filament formation in B. subtilis, using monomeric ParA/Soj that cannot bind DNA or hydrolyse ATP.

bioRxiv · Dec 18, 2021Microbiology

CTP regulates membrane-binding activity of the nucleoid occlusion protein Noc

A. S. B. Jalal, N. T. Tran, L. J. Wu, K. Ramakrishnan, M. Rejzek, G. Gobbato, C. E. M. Stevenson, D. M. Lawson, J. Errington, T. B. K. Le

This study shows that CTP regulates the membrane-binding activity of the nucleoid occlusion protein Noc in Bacillus subtilis by controlling its ability to form nucleoprotein complexes.

bioRxiv · Feb 11, 2021Microbiology

Geometric principles underlying the proliferation of a model cell system

L. J. Wu, S. Lee, S. Park, L. Eland, A. Wipat, S. Holden, J. Errington

This study investigates how cell geometry affects growth, chromosome segregation, and division in Bacillus subtilis L-forms, showing that surface area over volume and nucleoid positioning are key factors.

Nature Communications · Aug 18, 2020Peer-reviewedMicrobiology