Author

J. Pappalardo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Approach:deep learning· 2 Organism:human· 2 Approach:statistical model· 2 Approach:experimental assay· 1

Frequent Co-Authors

A. Chan· 1 shared A. Herman· 1 shared A. R. Munoz-Rojas· 1 shared C. Raposo· 1 shared C. Zografou· 1 shared D. A. Hafler· 1 shared D. Hafler· 1 shared E. E. Longbrake· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperImmunology

A. Chan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Systematic Analysis of Immune Changes after B-cell Depletion in Autoimmune Multiple Sclerosis

J. Wei, J. Moon, Y. Yasumizu, L. Zhang, K. Radassi, N. Buitrago-Pocasangre, M. E. Deerhake, N. Strauli, A. Chan, A. Herman, R. Pedotti, C. Raposo, I. Yim, J. Pappalardo, E. E. Longbrake, , D. A. Hafler

This study uses single-cell RNA sequencing to analyze immune changes after B-cell depletion in MS patients, revealing cell type-specific effects on macrophages, monocytes, and T cells.

bioRxiv · Feb 7, 2024 · PreprintImmunology

Co-stimulation with opposing macrophage polarization cues leads to orthogonal secretion programs in individual cells

A. R. Munoz-Rojas, I. Kelsey, J. Pappalardo, K. Miller-Jensen

This study shows that co-stimulation with opposing macrophage polarization cues leads to cell-to-cell heterogeneity in transcription and secretion programs.

bioRxiv · Apr 4, 2020Immunology

Single cell RNA sequencing reveals a novel, microglia-like cell type in cerebrospinal fluid during virologically suppressed HIV

S. Farhadian, S. Mehta, C. Zografou, J. Pappalardo, J. Chiarella, D. Hafler, S. Spudich

The paper uses scRNA-seq on cerebrospinal fluid from HIV patients to identify a rare microglia-like cell type associated with CNS immune activation.

bioRxiv · May 17, 2018Immunology