Author

M. E. Deerhake

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. Inoue· 2 shared M. L. Shinohara· 2 shared N. Aggarwal· 2 shared T. Nonaka· 2 shared W. E. Barclay· 2 shared A. Chan· 1 shared A. Herman· 1 shared C. Raposo· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

M. Inoue

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Author profile →

3 papers

Recent·Most cited

Systematic Analysis of Immune Changes after B-cell Depletion in Autoimmune Multiple Sclerosis

J. Wei, J. Moon, Y. Yasumizu, L. Zhang, K. Radassi, N. Buitrago-Pocasangre, M. E. Deerhake, N. Strauli, A. Chan, A. Herman, R. Pedotti, C. Raposo, I. Yim, J. Pappalardo, E. E. Longbrake, , D. A. Hafler

This study uses single-cell RNA sequencing to analyze immune changes after B-cell depletion in MS patients, revealing cell type-specific effects on macrophages, monocytes, and T cells.

bioRxiv · Feb 7, 2024 · PreprintImmunology

AIM2 inflammasome activation in astrocytes occurs during the late phase of EAE

W. E. Barclay, M. E. Deerhake, M. Inoue, T. Nonaka, K. Nozaki, N. A. Luzum, N. Aggarwal, E. A. Miao, M. L. Shinohara

This study identifies AIM2 inflammasome activation in astrocytes during the late phase of EAE, distinct from traditional inflammasome-mediated inflammation.

bioRxiv · Oct 3, 2021 · PreprintImmunology

Dectin-1 limits central nervous system autoimmunity through a non-canonical pathway

M. E. Deerhake, K. Danzaki, M. Inoue, E. D. Cardakli, T. Nonaka, N. Aggarwal, W. E. Barclay, R. R. Ji, M. L. Shinohara

This study shows Dectin-1 protects against CNS autoimmunity through a non-canonical pathway independent of Card9, promoting neuroprotective molecules like Osm in myeloid cells and reducing EAE severity via astrocytic OsmR signaling.

bioRxiv · May 6, 2020 · PreprintImmunology