Common drugs alter microbial protein expression, but not composition in fecal cultures from Crohn's disease patients
H. Becker, R. Mohren, G. Le, L. Derijks, D. Jonkers, J. Penders
bioRxiv · Aug 19, 2023 · PreprintMicrobiology
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H. Becker, R. Mohren, G. Le, L. Derijks, D. Jonkers, J. Penders
bioRxiv · Aug 19, 2023 · PreprintMicrobiology
C. Eriksen, N. B. Danneskiold-Samsoe, J. M. Moll, P. N. Myers, P. W. Bondegaard, S. Vejrum, T. B. Hansen, L. B. Rosholm, P. Rausch, K. H. Allin, T. Jess, K. Kristiansen, J. Penders, D. M. Jonkers, S. Brix
bioRxiv · Jun 30, 2023Immunology
B. Yousefi, F. Melograna, G. Galazzo, N. van Best, M. Mommers, J. Penders, B. Schwikowski, K. van Steen
The paper introduces MNDA, a framework for analyzing microbiome dynamics using individual-specific networks, showing improved prediction and subpopulation detection compared to traditional methods.
bioRxiv · Jan 22, 2023 · PreprintMicrobiology
H. E. Becker, N. Kameli, A. Rustichelli, F. R. Stassen, J. Penders, D. M. Jonkers
This study finds that faecal water from Crohn's disease patients shows higher mucin degradation in vitro but does not cause increased paracellular permeability.
bioRxiv · Aug 26, 2022 · PreprintMicrobiology
B. Vu Thi Ngoc, H. Ho Bich, G. Galazzo, D. Vu Tien Viet, M. Oomen, T. Nghiem Nguyen Minh, H. Tran Huy, R. Van Doorn, H. F. Wertheim, J. Penders
The paper analyzes the gut microbiota and environmental interactions in a Vietnamese household cohort, finding reduced diversity in antibiotic users and potential antimicrobial resistance gene exchange between humans and animals.
bioRxiv · Feb 23, 2021 · PreprintMicrobiology
B. C. van der Putten, J. M. van Hattem, J. Penders, COMBAT Consortium, D. R. Mende, C. Schultsz
This study identifies extraintestinal pathogenic E. coli (ExPEC) as more likely to persist in travelers' intestines for over 12 months compared to other E. coli lineages.
bioRxiv · Sep 23, 2020 · PreprintMicrobiology
H. E. F. Becker, C. Jamin, L. Bervoets, P. Xu, M. J. Pierik, F. R. M. Stassen, P. H. M. Savelkoul, J. Penders, D. M. A. E. Jonkers
This study finds higher Bacteroides fragilis prevalence in Crohn's disease exacerbations and shows that bft-positive strains increase intestinal epithelial resistance.
bioRxiv · May 16, 2020Microbiology
S. Matamoros, J. M. van Hattem, M. S. Arcilla, N. Willemse, D. Melles, J. Penders, T. Nguyen Vinh, H. Ngo Thi, COMBAT consortium, M. D. de Jong, C. Schultsz
The paper analyzes the global spread of the mcr-1 gene in E. coli and associated plasmids, finding high bacterial diversity but limited plasmid types responsible for gene transfer.
bioRxiv · Nov 2, 2017Microbiology