Author

R. van Doorn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Groenewoud· 1 shared A. J. van der Sluijs-Gelling· 1 shared B. Vu Thi Ngoc· 1 shared C. Roelse· 1 shared C. Salgado· 1 shared D. Vu Tien Viet· 1 shared E. B. Snaar· 1 shared F. B. Engel· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. Groenewoud

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Autoantibody subclass predominance is not driven by aberrant class switching or impaired B cell development

L. M. Paardekooper, Y. E. Fillie-Grijpma, A. J. van der Sluijs-Gelling, M. Zlei, R. van Doorn, M. H. Vermeer, M. Paunovic, M. J. Titulaer, S. M. van der Maarel, J. J. M. van Dongen, J. J. Verschuuren, M. G. Huijbers

The paper investigates why IgG4 autoantibodies predominate in certain autoimmune diseases and finds that B cell development is normal, suggesting antigen-driven subclass predominance rather than B cell dysfunction.

bioRxiv · Jun 30, 2023Immunology

Melanin enhances metastatic melanoma colonization by inhibiting ferroptosis

A. Groenewoud, G. Zhou, M. C. Gelmi, J. Yin, G. E. M. Lamers, R. van Doorn, R. M. Verdijk, M. J. Jager, F. B. Engel, E. B. Snaar

This study shows melanin protects melanoma cells from ferroptosis, enhancing metastasis, and suggests targeting melanin and ferroptosis could improve treatment of metastatic melanoma.

bioRxiv · Apr 3, 2023 · PreprintCancer Biology

Cross-sectional analysis of the microbiota of the human gut and their direct environment (exposome) in a household cohort in northern Vietnam.

B. Vu Thi Ngoc, H. Ho Bich, G. Galazzo, D. Vu Tien Viet, M. Oomen, T. Nghiem Nguyen Minh, H. Tran Huy, R. Van Doorn, H. F. Wertheim, J. Penders

The paper analyzes the gut microbiota and environmental interactions in a Vietnamese household cohort, finding reduced diversity in antibiotic users and potential antimicrobial resistance gene exchange between humans and animals.

bioRxiv · Feb 23, 2021 · PreprintMicrobiology

Interplay between TERT promoter mutations and methylation culminates in chromatin accessibility and TERT expression

C. Salgado, C. Roelse, R. Nell, N. Gruis, R. van Doorn, P. van der Velden

This study investigates how TERT promoter mutations and methylation interact to regulate TERT expression in healthy skin and melanoma cell lines.

bioRxiv · Nov 29, 2019Cancer Biology