Author

J. Pezzullo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J.-L. Giner· 2 shared A. G. Wagner· 1 shared A. Psaras· 1 shared B. Callahan· 1 shared B. P. Callahan· 1 shared C. Wang· 1 shared D. Ciulla· 1 shared D. F. Covey· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

J.-L. Giner

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2 papers

Recent·Most cited

Bioluminescence-based reporters for characterizing inhibitors and activators of human Sonic Hedgehog protein autoprocessing in live cells at high throughput.

D. Ciulla, P. Dranchak, J. Pezzullo, R. Mancusi, A. Psaras, G. Rai, J.-L. Giner, J. Inglese, B. Callahan

This paper develops a bioluminescence-based reporter system to monitor human SHhC autoprocessing in live cells for high-throughput screening of inhibitors and activators.

bioRxiv · Jun 27, 2022Biochemistry

Nanomolar, noncovalent antagonism of hedgehog cholesterolysis: exception to the irreversibility rule for protein autoprocessing inhibition.

A. G. Wagner, R. T. Stagnitta, Z. Xu, J. Pezzullo, N. Kandel, D. F. Covey, J.-L. Giner, C. Wang, B. P. Callahan

The paper identifies noncovalent, reversible inhibitors of HhC cholesterolysis, challenging the irreversibility rule for protein autoprocessing inhibition.

bioRxiv · Sep 1, 2021Biochemistry