Lifelong Ulk1-mediated autophagy deficiency in muscle induces mitochondrial dysfunction and contractile weakness
A. S. Nichenko, J. R. Sorensen, W. M. Southern, A. E. Qualls, A. G. Schifino, J. McFaline-Figueroa, J. E. Blum, A. E. Thalacker-Mercer, S. M. Greising, J. A. Call
This study shows that lifelong Ulk1-mediated autophagy deficiency in muscle leads to mitochondrial dysfunction and contractile weakness in aging.
bioRxiv · Jul 31, 2020Physiology