Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes
B. Arragain, G. Effantin, P. Gerlach, J. Reguera, G. Schoehn, S. Cusack, H. Malet
This study presents the cryo-EM structures of La Crosse virus polymerase in pre-initiation and elongation states, revealing conformational changes important for transcription.
Nature Communications · Jul 17, 2020Peer-reviewedBiophysics