Author

B. Arragain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:cryo-EM· 3 Research Focus:host-pathogen & immune response· 2 Approach:microscopy & imaging analysis· 2 Research Focus:protein structure prediction· 2 Organism:virus· 2 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

H. Malet· 3 shared G. Schoehn· 2 shared S. Cusack· 2 shared S. CusackiD· 2 shared A. Thompson· 1 shared C. Isel· 1 shared D. Housset· 1 shared F. Baudin· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersBiochemistry

H. Malet

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structural characterization of the oligomerization of full-length Hantaan virus polymerase into symmetric dimers and hexamers

Q. Durieux Trouilleton, D. Housset, B. Arragain, H. Malet

This study characterizes the oligomerization of Hantaan virus polymerase into dimers and hexamers using cryo-EM, revealing structural changes upon RNA binding.

bioRxiv · Oct 4, 2023Biochemistry

Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family

B. Arragain, M. Pelosse, A. Thompson, S. Cusack

This study characterizes the structure and function of the minimal orthomyxovirus-like polymerase from Tilapia Lake Virus, revealing its active domains and inactive features.

bioRxiv · Aug 14, 2023 · PreprintMicrobiology

The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome

T. Krischuns, B. Arragain, C. Isel, S. Paisant, M. Budt, T. Wolff, S. Cusack, N. Naffakh

This study shows that host RNA polymerase II's C-terminal domain, along with ANP32, enhances influenza virus polymerase replication activity, suggesting host RNAP II anchors viral transcription and replication.

bioRxiv · Aug 1, 2023Microbiology

Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription

B. Arragain, Q. D. Trouilleton, F. Baudin, S. Cusack, G. Schoehn, H. MALET

This study uses cryo-EM to reveal the structural dynamics of La Crosse virus polymerase, elucidating mechanisms of replication and transcription in Peribunyaviridae.

bioRxiv · Jul 20, 2021Microbiology

Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes

B. Arragain, G. Effantin, P. Gerlach, J. Reguera, G. Schoehn, S. Cusack, H. Malet

This study presents the cryo-EM structures of La Crosse virus polymerase in pre-initiation and elongation states, revealing conformational changes important for transcription.

Nature Communications · Jul 17, 2020Peer-reviewedBiophysics