ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1
J. Rincon-Torroella, M. Dal Molin, B. Mog, G. Han, E. Watson, N. Wyhs, S. Ishiyama, T. Ahmedna, I. Minn, N. S. Azad, C. Bettegowda, N. Papadopoulos, K. W. Kinzler, S. Zhou, B. Vogelstein, , S. Sur
ME3BP-7 is a novel 3BP formulation that resists serum degradation and kills MCT1-high pancreatic cancer cells with low toxicity in mice.
bioRxiv · Jul 23, 2023Cancer Biology