Author

S. Ishiyama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:behavioral assay· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1 Organism:rat· 1

Frequent Co-Authors

A. Maejima· 1 shared A. Tsugita· 1 shared B. Mog· 1 shared B. Vogelstein· 1 shared C. Bettegowda· 1 shared C. Gatsogiannis· 1 shared D. DeAngelo· 1 shared E. Watson· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

A. Maejima

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural basis for bispecific antibody design: arrangement of domain linkage produces activity enhancement

K. Sato, S. Uehara, A. Tsugita, S. Ishiyama, A. Maejima, I. Nakahara, M. Nazuka, T. Matsui, C. Gatsogiannis, T. Yokoyama, I. Kumagai, K. Makabe, R. Asano, Y. Tanaka

This study determines the cryo-EM structures of two bispecific antibody types and shows that domain linkage rearrangement leads to activity enhancement by altering complex shape and dynamics.

bioRxiv · Apr 25, 2024 · PreprintBiochemistry

Comparative Analysis of Tickling and Conspecific Play in Tame Mice and Golden Hamsters

S. Dagher, D. DeAngelo, R. Y. Sato, H. Norimoto, T. Koide, S. Ishiyama

This study compares social play behavior in tame mice and golden hamsters during interactions with humans and conspecifics, finding differences in vocalization and interaction patterns.

bioRxiv · Mar 19, 2024Animal Behavior & Cognition

ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1

J. Rincon-Torroella, M. Dal Molin, B. Mog, G. Han, E. Watson, N. Wyhs, S. Ishiyama, T. Ahmedna, I. Minn, N. S. Azad, C. Bettegowda, N. Papadopoulos, K. W. Kinzler, S. Zhou, B. Vogelstein, , S. Sur

ME3BP-7 is a novel 3BP formulation that resists serum degradation and kills MCT1-high pancreatic cancer cells with low toxicity in mice.

bioRxiv · Jul 23, 2023Cancer Biology