J. Roel-Touris

Design of extended metal-binding β-sandwiches from de novo immunoglobulin domains

This paper designs extended β-sandwiches from de novo immunoglobulin domains, showing high stability and metal-binding affinity, and proposes scaffolds for multiple loop binding sites.

De Novo Design of Immunoglobulin-like Domains

This paper introduces design rules for immunoglobulin-like domains and demonstrates the de novo creation of stable, functional scaffolds with improved biophysical properties.