Author

J. Roelofs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Organism:yeast· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

K. A. Waite· 3 shared G. Vontz· 2 shared A. Burrris· 1 shared A. Kante· 1 shared A. Lang· 1 shared E. J. Deeds· 1 shared S. Y. Lee· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

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3 shared papersCell Biology

K. A. Waite

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Author profile →

4 papers

Recent·Most cited

In vitro reconstitution of the M.tb proteasome core particle reveals conserved aspects of bacterial proteasome assembly

A. Kante, J. Roelofs, E. J. Deeds

This study reconstitutes the M.tb proteasome core particle in vitro, revealing conserved assembly pathways across bacteria and enabling inhibitor screening.

bioRxiv · Jul 5, 2023 · PreprintBiochemistry

Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains

K. A. Waite, G. Vontz, S. Y. Lee, J. Roelofs

This paper identifies that proteasome condensates in yeast form via multivalent interactions involving K48-linked ubiquitin chains, shuttle factors Rad23 and Dsk2, and proteasome receptors, suggesting functional specificity in condensate formation.

bioRxiv · Jun 25, 2023 · PreprintCell Biology

Proteasome granular localization is regulated through mitochondrial respiration and kinase signaling

K. A. Waite, J. Roelofs

The paper investigates how mitochondrial respiration and kinase signaling regulate proteasome localization in yeast, finding that mitochondrial activity influences proteasome granule formation.

bioRxiv · Jan 13, 2022Cell Biology

Proteasome autophagy is specifically regulated and requires factors dispensible for general autophagy

K. A. Waite, A. Burrris, G. Vontz, A. Lang, J. Roelofs

The paper investigates proteasome autophagy regulation, showing it is distinct from general autophagy and requires specific factors like Atg11 and map kinases.

bioRxiv · Mar 26, 2021Biochemistry